Thursday, 5 December 2013

Resistant hypertension uncommon in China

by Michael Woodhead
The rate of resistant hypertension in China is much lower than previously thought, research from Beijing suggests.
Cardiologists from the Division of Hypertension, FuWai Hospital and Cardiovascular Institute, Peking Union Med College, made an analysis of resistant hypertension based on data from the Hypertension Optimal Treatment Study in China.
The study was conducted in 148 cities in mainland China in 2001- 2002 and included 54 590 hypertensive adult. Patients not achieving blood pressure (BP) target (<140/90 mmHg) within two weeks received preplanned additional drugs. Resistant hypertension was defined in the participants with uncontrolled hypertension after two weeks of treatment on Step 5.
The study found the rate of resistant hypertension was 1.9%. Patients with resistant hypertension tended to be male and younger than average be overweight and have metabolic syndrome, diabetes mellitus and history of myocardial infarction or stroke.
Study author Dr Ma Wenjun said the rate of resistant hypertension in China was much lower than the levels of around 20% previously reported by groups such as the AHA. This might be because the trial follow up period was relatively short and because a rigorous regimen of BP treatment and adherence was adopted. Neverthless, the finding that resistant BP was uncommon and occurred more in younger pateints deserves further attention, he said.
Full study: Journal of Hypertension

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