Thursday, 12 December 2013

Reference values for bone mineral density developed for Chinese infants

Clinicians from Hubei have developed reference values for lumbar bone mineral density in healthy Chinese infants and young children. 
In a study of almost 12,000 healthy children aged 0 to 3 years who underwent regular physical examinations at the Child Health Care Clinic of Hubei Maternal and Child Health, researchers obtained BMD measurements of the lumbar spine (L2–L4) with dual-energy X-ray absorptiometry and a questionnaire. They also obtained BMD values for 379 preterm infants The results showed that lumbar BMD significantly increased with age among both boys and girls, with fastest growth observed during the first postnatal year. There was no significant difference in lumbar BMD between boys and girls of similar age, either among healthy reference children or preterm infants. However, BMD values in preterm infants were significantly lower than those in term infants 3 to 8 months old after adjustment for gestational age.
There were significant positive associations between lumbar BMD of healthy children and the child's age and current weight, mother's weight gain during pregnancy, birth weight, children's outdoor activity duration and children's physical activity duration.
Source: PLOS One

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