Friday, 4 January 2013

China clinical news in brief

Infant gastro infections may trigger convulsions

Benign convulsions may occur in infants with mild gastroenteritis, Chinese paediatricians have shown.
Dr Wang Yunfeng of the Department of Pediatrics at the Sino-Japan Friendship Hospital, Beijing says that benign convulsions are now recognized as a distinct clinical entity in many countries, but its occurrence in China has not yet been widely recognized by Chinese pediatricians.
In a retrospective study  in 48 infant patients with benign convulsions they found that the typical age of onset of gastroenteritis was between 13 months and 24 months. The episodes of convulsions occurred at a distinct autumn/winter peak, and the seizures mostly occurred within the first five days of gastroenteritis, especially within the first three days, peaking on day 2 (39.58%).
They found that in 80% of cases the infants had clustered seizures in their episodes. Most episodes were symmetric, generalized tonic-clonic  and brief. The seizures were induced by pain and/or crying in 40% of infants. Stool culture was positive for rotavirus in 54% of the patients. Almost half the infants still had clustered seizures after the administration of a single anticonvulsant drug. The seizures persisted even after the administration of two combined anticonvulsants in a quarter of episodes. All patients exhibited normal psychomotor development.
"Benign convulsions with mild gastroenteritis are not rare in China, and rotavirus infection is a major cause," the researchers conclude.
Source: World Journal of Paediatrics


MSG linked to snoring and sleep disordered breathing

People who consume MSG with their food are more prone to snoring and sleep disordered breathing, researchers from Nanjing have shown.
An analysis of data from 1227 Chinese people who participated in the Jiangsu Nutrition Study found that MSG intake was positively associated with snoring and a high probability of sleep disordered breathing such as sleep apnoea.
However, the association was not seen in in overweight people, according to Dr Shi Zumin and co-researchers at the Department of Nutrition and Foodborne Disease Prevention, Jiangsu Provincial Centrr for Disease Control and Prevention, Nanjing.
People who had higher intakes were twice as likely to snore and three times more likely to have sleep apnoea, the study showed..
Source: Nutrition Journal


One in three people with diabetes have chronic kidney disease

Almost one in three Chinese people with type 2 diabetes have chronic kidney disease and albuminuria, a Nanjing study has found.
Dr Lou Qing-Lin and co-researchers from the Diabetes Care and Research Centre at the Jiangsu Province Institute of Geriatrics conducted a study of more than 15000 patients with type 2 diabetes in Nanjing between January 2008 and December 2009.
They found that the frequency of CKD and albuminuria was 31% and 29%, respectively.
Hypertension, anaemia and duration of diabetes were significantly associated with CKD.
"In conclusion, chronic kidney disease is common in the urban Nanjing Chinese with type 2 diabetes. Strategies to prevent or delay progression of kidney disease in diabetes should be carried out at the early disease course of type 2 diabetes," they conclude.
Source: Diabetes and Metabolism Journal

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