Friday, 30 November 2012

Vaccine adverse reaction no higher in China than other countries


by Michael Woodhead
A review of vaccine-related adverse effects in China has found hat rates are in line with those seen in other countries.
Researchers from the National Immunisation Program, Chinese Centre of Disease Control and Prevention, Beijing, found that overall rates of adverse events following immunisation (AEFI)  in China were in line with other health systems, though there was considerable regional variation. Rates of adverse events ranged from 2.3–38/100,000 doses.
As in other countries, the highest rates of adverse events were seen after immunisation with diphtheria–tetanus–pertussis (whole-cell) vaccine  and DTP (acellular) (DTaP) vaccines. Lower rates of adverse events were seen for vaccines against hepatitis B virus, poliovirus, and Japanese encephalitis virus.
"Overall adverse events following immunisation  reporting rates in China were consistent with similar post-marketing surveillance systems in other countries. Sources of regional heterogeneity in AEFI reporting rates and their relationships to differing vaccine manufacturers versus differing surveillance practices, and safety of key vaccines suggested higher reporting rates require further exploration," the researchers conclude.
Read more: Vaccine.

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